Simran was born into a Punjabi family in Mumbai. She began her career as a model and appeared in several television commercials. Her entry into the film industry was with the 1995 Tamil film "Varmam," but it was her role in the 1999 film "Chennai Express" that gained her recognition.

Simran was often the lucky charm for leading heroes.

“Kathi – Simran’s Courtroom Monologue” Scene: As Vijay’s mother, she delivers a fiery speech against land encroachment. This marked her powerful return after a hiatus.